Bay IVF - Advanced Reproductive Care                                Palo Alto  650-322-0500


Deciding Between Minimal IVF And Conventional IVF

The majority of eligible patients will be candidates for both conventional In Vitro Fertilization and Mini-IVF.

The following table summarizes the differences between Minimal IVF and conventional IVF.

Mini-IVF and Conventional IVF
Treatment Comparison
  Mini-IVF Conventional
Live-Birth Probability
Per Embryo Transfer
  • Identical/similar
  • Identical/similar
Live-Birth Probability from
All Available Embryos
  • Will be lower
    (fewer embryos available for repeated transfers)
  • Should be higher
    (more embryos available for repeated transfers)
$6,920 $11,870
Cost of
  • Approx. $1,500+
    (charged by a pharmacy)
  • Approx. $3,500+
    (charged by a pharmacy)
  • 40 years and younger
  • Weight 150lb or less
  • 21 to 35-day menstrual cycles
  • AFC1 10 to 24
  • FSH 9.0 or less and E2 50 or less2
  • AMH between 1.5 and 4.0 inclusive3
  • Min. sperm motility: 5% and min. nl morphology: 5%4
  • 43 years and younger
  • BMI 29 or less
  • Regular menstrual cycles are not required
  • AFC 4 or higher
  • FSH 15.0 or less and E2 90 or less
  • Any AMH level
  • Any number of living sperm
  • Daily tiny, shallow injections for approx. 10 days
  • Approx. 2 blood draws
  • Daily tiny, shallow injections for approx. four weeks
  • Approx. 5 blood draws
Egg Retrieval
  • Identical/similar
  • Identical/similar
Embryo Transfer
  • Identical/similar
  • Identical/similar
Number of
Clinic Visits
  • Approx. 2 to 4
  • Approx. 4 to 6
Can Be Combined with Sperm Aspiration
  • No
  • Yes, if needed


1 You will have an ovarian ultrasound during your initial visit at Bay IVF to count the number of antral follicles, seen as small dark circles, within the ovaries (AFC, antral follicle count). 

The AFC is related to the quality of the eggs. Ideally, there should be approximately 20 antral follicles in both ovaries combined. Too few or too many antral follicles indicate that normal-quality eggs may be infrequent or even absent within the ovaries.

There must be between 10 and 24 antral follicles in both ovaries combined for Mini-IVF. Women with too low or too high AFC do not properly respond to Mini-IVF ovarian stimulation. The majority of women will have 12 to 24 antral follicles.


2 FSH = follicle stimulating hormone, E2 = estradiol, estrogen

3AMH (Anti-Müllerian hormone) level reflects the quality of eggs; the result should ideally be between 2 and 3. Lower or substantially higher levels signify less than optimal egg quality.

The AMH level must be between 1.5 and 4.0 inclusive for Mini-IVF. Women with very low or very high AMH levels are not good candidates for Mini-IVF ovarian stimulation and should consider conventional In Vitro Fertilization.

4 Since the average number of retrieved eggs is expected to be lower in the Mini-IVF treatment compared with conventional IVF, there must not be a major degree of male infertility

 The male partner must be able to produce a sufficient number of living sperm (total motility 5% or higher and normal sperm morphology 5% or higher in the preliminary semen analysis at Bay IVF). This minimizes the risk that none of the eggs will fertilize.

If you have any questions regarding the above information or need help deciding between conventional IVF and Minimal IVF, please contact us by phone at 650-322-0500 or via email at

Please use the following links for additional information about Minimal stimulation IVF and to request a consultation.



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